脑磁图对致灶定位的临床应用价值

Clinical application value of magnetoencephalography in localizatin of epileptogenic foci

目的 :探讨脑磁图 (MEG)对致灶定位的临床应用价值。方法 :对临床诊断为癫的 2 5例病人进行MEG检查 ,并与磁共振图 (MRI)、脑电图 (EEG)及术中脑皮层电图 (ECoG)作比较。结果 :2 5例接受MEG检查者中 ,2 2 (88% )例可确定出致灶 ,其中 18例 (72 % )得到ECoG证实 ,4例部位不相符。另外 3例MEG未发现致灶者 ,深部电极EEG则在颞叶前内侧描记到样放电。MEG结果与ECoG对照 ,符合率为 72 %。结论

Objective: To explore the clinical application value of magnetoencephalography (MEG) in the localization of epileptogenic foci. Methods: MEG was done in twenty-five patients with epilepsy diagnosed clinically and the results were compared with MRI,EEG and intraoperative ECoG monitoring.Results: Epileptogenic foci were determined by MEG in 22 patients and 18 ones of them were comfirmed by ECoG,but not corresponding in 4 cases.No epileptogenic foci were found in 3 ones by MEG,whereas epileptiform discharges were detected on mesial temporal lobe by depth-electrode recording intraoperatively.The rate of correspondance with ECoG was 72% in localization of epileptogenic foci by MEG.Conclusion:MEG might be of important clinical application value in the localization of epileptogenic foci in superfacial cortex.