我院2001年抗菌药物的应用分析

Analysis of antimicrobial application of Kunming General Hospital of Chengdu Military Command of PLA in 2001

目的:探讨抗菌药物在临床的合理应用。方法:①以我院2001年1月-12月抗菌药物的发放记录作为原始资料进行统计分析。②用本院自行开发设计的《计算机预警系统软件》提取相关病例340例,进行药物不良反应分析。结果:青霉素类使用频率最高,用量最大;喹诺酮类、克林霉素、氨基糖类较为常用;48例抗菌药引起的不良反应,以青霉素类出现的例数最多,其次为喹诺酮类和头孢菌素类。结论:通过药物安全性检测及对ADR相关费用的测算分析,有助于减少ADR,并降低治疗费用,提高本院抗菌药物应用水平。

OBJECTIVE: To check out whether antibacterial drugs were rational in clinical use. METHODS: Original data of antibacterial drugs were statistically analyzed and using a self - design software, we carried out a comprehensive analysis of adverse drug reaction of 340 cases. RESULTS: The frequency of penicillin use is the highest, Quinolones, clindamycins and aminogiycosides were mostly used. Of 48 adverse drug reaction cases, ADRs caused by penicillin ranked the first, Quinolones ranked the second and Cefazolins ranked the third. CONCLUSION : It would be helpful to decrease the occurrence of ADR and the cost of ADR and improve the use of antibacterial drugs.