尼麦角林治疗多发梗死性痴呆临床观察

A Clinical Observation on the Effect of Nicergoline in the Treatment of Multi-infarct Dementia

目的 :观察尼麦角林对多发梗死性痴呆认知功能障碍的疗效。方法 :3 2例多发梗死性痴呆患者均口服尼麦角林 10mg ,tid ,连服 3个月为 1疗程。结果 :多发梗死性痴呆患者认知功能MMSE评分治疗后较治疗前显著提高 (P <0 .0 1) ,认知功能改善的总有效率 84.4%。结论 :尼麦角林对改善多发梗死性痴呆认知功能障碍具有较好的疗效。

Objective:To survey the therapeutic effect of nicergoline (Sermion) on the disorder of cognitive function in patients with multi infarct dementia (MID). Method:32 patients with MID were given each nicengoline at a dosage of 10 mg t.i.d. per os for 3 consecutive months. Results:The mean MMSE score reflecting the cognitive function of the patients with MID was significantly increased ( P <0.01) after nicergoline treatment, as compared with that before the treatment. The total effective rate was 84.4%. Conclusion:Nicergoline was shown to be an effective drug for improving the cognitive function of patients with MID.