酮咯酸氨丁三醇治疗外科疾病疼痛118例

Ketorolac Tromethamine in the Treatment of Pain in 118 Patients with Surgical Diseases

目的 :探讨酮咯酸氨丁三醇对外科疾病疼痛的镇痛效果。方法 :外科疾病疼痛患者 118例 ,给予酮咯酸氨丁三醇注射液 3 0mg ,im ,口服剂 10～ 2 0mg ,po ,每天最大剂量不超过 12 0mg ,对剧烈疼痛给药 3 0min后无效者 ,可再肌内注射 3 0mg。结果 :起效时间 5～ 60min ,平均 3 5min ,止痛时间为 0 .5～ 2 4h ,平均 8.2h。总有效率 97.5 %。结论 :酮咯酸氨丁三醇镇痛抗炎作用显著 ,并且起效迅速 ,可用于临床各种外科性疼痛。

Objective:To study the analgesic effect of ketorolac tromethamine (KT) in the treatment of pain in patients with surgical diseases. Method:118 patients complaining of pain due to surgical diseases served as the subjects of the study. To each of these cases, 30 mg of KT were administered i.m. and 10-20 mg p.o.. The maximum daily dosage was not allowed to exceed 120 mg. Patients with severe pain that could not be relieved 30 min after the first medication were given each an additional dose of 30 mg of KT i.m. Results:The time of initiation of the effect was 5-60 min, with an average of 35 min. The analgesic effect lasted 0.5-24 h, with a mean of 8.2 h. The overall effective rate was 97.5% (115/118). Conclusion:Ketorolac tromethamine was shown to have a striking analgesic effect. The drug also started to act very soon. It is therefore suggested by the authors to use the drug for relieving pain associated with different clinical diseases.