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Northern印迹法检测喉鳞状细胞癌中表皮生长因子受体mRNA的表达 被引量:4

The expression of epidermal growth factor receptor mRNA in the laryngeal squamous cell carcinoma with Northern Blot
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摘要 目的 :探讨喉部鳞状细胞癌的发病机制。方法 :采用Northern印迹法检测喉部鳞状细胞癌中表皮生长因子受体mRNA的表达。结果 :在喉部鳞状细胞癌中可见 5 80 0mRNA异常表达。结论 :喉部鳞状细胞癌的生物学行为与其 5 80 0mRNA介导异常表达密切相关。 Objective:To explore the mechanism of the origin of laryngeal squamous cell carcinoma. Method:Northern Blot was used. Result:The abnormal expression of EGF R mRNA ( 5.8 kb) was found in the laryngeal squamous cell carcinoma. Conclusion:The uncontrolled cell growth and proliferation of the laryngeal squamous cell carcinoma may be related to the abnormal expression of EGF R mRNA( 5.8 kb ).
作者 符征 汪吉宝
出处 《临床耳鼻咽喉科杂志》 CAS CSCD 北大核心 2002年第12期648-649,共2页 Journal of Clinical Otorhinolaryngology
关键词 Northern印迹法 检测 喉鳞状细胞癌 表皮生长因子受体 MRNA 表达 Laryngeal squamous cell carcinoma Epidermal growth factor receptors Blotting, northern
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