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胰岛干细胞研究进展 被引量：3

Recent progress in study of pancreatic stem cell
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摘要 胰岛干细胞移植是治疗糖尿病的一条新途径 ,它可避免胰岛移植治疗糖尿病所面临的胰腺供体匮乏及长期使用免疫抑制剂而产生严重副作用的问题。本文将对有关胚胎干细胞及成体干细胞诱导分化为胰岛素分泌细胞 ,胰岛干细胞的分子标志 。 Transplantation of pancreatic stem cells as a new therapy for diabetes mellitus will substitute transplantation of islets , because it avoids problems from lacking of sufficient donor pancreas and the side effects of immunosuppressive therapy which are the major drawbacks for transplantation of islets . Our review briefly summarized recent progress in insulin secreting cells induced from embryonic stem cells and adult stem cells. We also discussed the specific markers for identification and the present status of the clinical application of pancreatic stem cells.
作者 杨锋 张世馥
机构地区 中国协和医科大学中国医学科学院基础医学研究所
出处 《基础医学与临床》 CSCD 北大核心 2002年第5期397-403,共7页 Basic and Clinical Medicine
关键词 胰岛干细胞 糖尿病 胰岛素分泌细胞 临床应用 pancreatic stem cell diabetes
分类号 R587.1 [医药卫生—内分泌]
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共引文献53

同被引文献47

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基础医学与临床
2002年 第5期

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