聚甲酚磺醛联合抗宫炎片治疗宫颈糜烂的临床疗效观察

Clinical curative effect investigation of treating cervical erosion by policresulen combined with anti-hysteritis tablet

目的 :观察聚甲酚磺醛联合抗宫炎片治疗宫颈痰烂的疗效。方法 :将 397例经宫颈细胞学检查 ,阴道分泌物检查排除恶变、霉菌及滴虫的宫颈糜烂患者随机分为 2组 ,联合用药组 2 0 0例 ,宫颈糜烂局部使用聚甲酚磺醛浓缩液 ,每周 2次 ,同时加服抗宫炎片 4片 ,tid。单用药组 197例 ,宫颈糜烂局部使用聚甲酚磺醛浓缩液 ,每周 2次。结果 :宫颈糜烂Ⅰ ,Ⅱ ,Ⅲ度分别治疗 2 ,4,6wk后 ,宫颈糜烂面修复有效率 ,联合用药组分别为 98 8% ,92 7% ,75 0 % ;单用药组分别为 98 8% ,92 9% ,72 7%。 2组比较 ,无显著性差异 (P >0 0 5 )。联合用药组和单用药组的腰酸、腹痛改善者分别为 97 6 %和 91 6 % (P <0 0 5 ) ,白带减少者分别为 97 0 %和 91 3% (P <0 0 5 )。结论 :聚甲酚磺醛不仅局部疗效明确 ,而且能缓解临床症状 ,如加服抗宫炎片 。

AIM: To observe and compare the curative effect of treating cervical erosion by policresulen combined anti-hysteritis tablet and policresulen only. METHODS: Three hundred and ninety-seven patients with cervical erosion without latent cancer, fungus and trichomoniasis were randomly divided into 2 groups. Two hundred patients in combined therapy group treated by policresulen combined with anti-hysteritis tablet. Policresulen condensed liquid was used in cervical erosion part twice one week and 4 anti-hysteritis tablet was taken, tid. One hundred and ninety-seven patients in single use of policresulen group treated by policresulen only. Policresulen condensed liquid was used in cervical erosion part twice one week. RESULTS: After 2,4 and 6 wk treatment for the patients of cervical erosion Ⅰ, Ⅱ, Ⅲ, the efficiency rates of cervical erosion repair were 98.8%, 92.7%, 75.0%, respecively for combined therapy group and 98.8%, 92.9%, 72.7%, respectively for single use of policresulen group with no remarkable difference (P>0.05). Clinical symptoms including pain of waist and abdomen and leukorrhagia were improved. The effective rate were 97.6% and 97.0% respectively for combined therapy group and 91.6% and 91.3% for single use of policresulen group with obvious difference (P<0.01). CONCLUSION: Policresulen is curatively valid not only in part but also in clinical symptom. The curative effect is better by policresulen combined with anti-hysteritis tablet than by policresulen only.