摘要
探讨生物制品冻干粉针剂样品放置一段时间后残余水分增高的原因。进行了水分测定、真空度检测、二甲硅油和丁基橡胶药用瓶塞干燥失重的检测。冻干后每只丁基橡胶药用瓶塞平均含水分 0 .0 0 2 2 4g。结果表明丁基橡胶药用瓶塞灭菌。
To study the causes of increasing moisture content in freeze dried powder of biological products after been laying a period by moisture control test, the tests for moisture content,vacuum weight loss on drying of dimethicone and rubber stopper of vial were performed. Average moisture content of a rubber stopper was 0.00224g after freeze-dried. The increasing moisture content of samples was due to the incompletely removal of the moisture of rubber stopper during sterilizing, drying and freeze-drying process.
出处
《微生物学免疫学进展》
2002年第4期44-47,共4页
Progress In Microbiology and Immunology
