三种方法预防术后恶心呕吐效果的比较

Comparisons of three methods for prevention of nausea and vomit after operation

目的 观察三种方法预防术后恶心呕吐 (PONV)的效果。方法 选择 80例美国麻醉医师协会 (ASA)体检标准分类Ⅰ～Ⅱ级上腹部以下手术患者 ,随机分为三组 ,硬膜外麻醉 ,静脉给药 :一组 40例 ,给予枢丹 8mg ;二组 2 0例 ,给予胃复安 10mg ;三组 2 0例 ,给予氟哌利多 5mg。观察三组PONV的发生率。结果 PONV发生率一组为 3例 (7.5 % ) ,二组 7例 (35 % ) ,三组 7例 (30 % ) ,一组与二、三组比较差异有显著性 (P <0 .0 5 )。结论 枢丹较之胃复安及氟哌利多更能有效的预防术后恶心。

Objective To observe the effectiveness of three methods for post-operation nausea and vimitting(PONV).Methods A total of 80 cases with upper abdominal operation of grade Ⅰ Ⅱ were selected and divided into three groups,being 40 cases in Group One,20 cases in Group Two and another 20 in Group Three.All the cases in the three groups were treated with epidural anaesthesia,and then 8 mg of ondansetron was given cases in Group One,10mg of metoclopranmize was given to Group Two and 5mg of droperidol was given to those in Group three.Results The results show that the incidence of PONV occurred to 3 cases in Group One(7.5%),7 cases in Group Two(35%) and 7 cases in Group Three.Significant differences were observed in the incidence of PONV between the Groups.Conclusion Ondansetron was more effective than metoclopramize and droperidol for preventing PONV.