主动按压减压结合高频通气对心肺复苏犬的循环效应影响

The influence of active compression-decompression combined with high frequency jet ventilation on the hemodynamic response of cardiopulmonary resuscitation in dogs

目的 比较标准心肺复苏、主动按压减压心肺复苏、主动按压减压结合高频通气心肺复苏三种复苏法对心肺复苏循环效应影响 ;评价主动按压减压结合高频通气用于心肺复苏的可行性。方法 将9条犬经电击致颤制成心搏骤停模型 ,每只犬先后实施三种复苏法 ,①标准心肺复苏 ;②主动按压减压心肺复苏 ;③主动按压减压结合高频通气心肺复苏 ,实验顺序由随机法确定 ,每种复苏方法进行 5min ,待循环动力学稳定后记录收缩压、舒张压、心输出量。结果 收缩压、舒张压、心输出量均为主动按压减压结合高频通气模式大于主动按压减压心肺复苏模式 (P <0 0 1) ;主动按压减压心肺复苏模式大于标准心肺复苏模式 (P <0 0 1)。标准心肺复苏模式和主动按压减压心肺复苏模式胸外按压停顿期血压降至零 ,而主动按压减压结合高频通气心肺复苏模式血压持续稳定。结论 主动按压减压心肺复苏优于标准心肺复苏模式。主动按压减压结合高频通气心肺复苏模式既可产生较高的动脉血压、心输出量 ,又可提供充分的气体交换 。

Objective To compare the hemodynamic response of standard CPR (S CPR),active compression decompression CPR(ACD CPR) and ACD CPR combined with high frequency jet ventilation (ACD H),and to evaluate feasibility of ACD H.Methods Each of the 9 dogs with cardiac arrest induced by electrical shock received S CPR,ACD CPR,and ACD H.The sequence of CPR was random.Each CPR lasted 5min.After the hemodynamics was stable,the readings of arterial systolic pressure,arterial diastolic pressure,and cardiac output were recorded.Results The systolic pressure,diastolic pressure,and cardiac output in ACD H were higher than those in ACD CPR.The systolic pressure,diastolic pressure and cardiac output in ACD CPR were higher than those in S CPR.Arterial pressure in S CPR and ACD CPR was zero during the ventilation phase.Arterial pressure in ACD H remained stable.Conclusion ACD CPR was superior over S CPR.ACD H can provide higher arterial pressure,cardiac output and adequate ventilations. [