转生长激素基因鲤的快速生长效应及传代

The faster growth effect of transgenic common carp with growth hormone gene and its progenies

报道了转生长激素基因鲤阳性群体的建立和"超级鲤"的获得。给出了"超级鲤"和对照组连续4年的生长实验结果及"超级鲤"子代连续3年的生长对照的体重数据。结果显示,外源生长激素基因对受体鲤具有快速生长效应,但具有这种超速生长作用的个体在转基因鲤群体中占极少数。此效应能传递给子代,子代中快速生长个体的比例大大高于转基因实验群体。

A big group of transgenic Cyprinus carpio with salmon growth hormone gene was constructed. A 'super fish' with very faster growth rate was selected from more than 10 000 transgenic common carps. The results of four years sequential growth experiments of the 'super fish' and its controls were reported. The result of three years sequential growth experiments of the progenies of the 'super fish' was reported, and the data of the weight of those progenies and their controls were also reported here. The statistical analysis of those data showed that the effect of salmon growth hormone gene for the transgenic common carp was positive, but only a few in those transgenic fish with this faster growth effect. The weight of the 'super' fish was about two times the weight of the biggest fish in control. The faster growth effect could be transmitted to next generation, and the ratio of faster growth fish in progenies was much higher than that in transgenic Cyprinus carpio population. 43% progenies had foreign genes, but only 14% progenies had the fast growth feature and kept this fast growth trait in their three year old. Some progenies was 5 kg at three year old. In the paper, the future of transgenic fish was also discussed. Gene transfer is a very powerful tool for scientists to create new aquaculture species with good trait, although this technique needs to be developed further. Gene transfer methods will benefit from other basic researches such as genome research and molecular biology technology. Transgenic fish would be used in farm after it is tested to be no harm to ecosystem and human beings. For this, more researches on ecosystem testing should be done from now on.