血清总胆汁酸检测在脑血管疾病中的临床意义

Clinical Significance of Examining Serum Total Bile Acids in Cerebral Vascular Diseases

目的 探讨血清总胆汁酸 (TBA)测定在脑血管疾病诊断中的临床意义。方法 采用酶法检测脑梗塞患者2 9例 ,脑出血患者 2 6例及非心脑血管疾病患者 30例中血清 TBA及血脂水平。结果 脑梗塞组 TBA水平显著高于对照组和脑出血组 (t=6 .78,3.4 0 ,P<0 .0 1) ,脑出血组 TBA水平也显著高于对照组 (t=3.87,P<0 .0 1)。结论 脑梗塞和脑出血与血清 TBA水平呈正相关 ,TBA测定有助于脑梗塞和脑出血的鉴别诊断。

Objective To study clinical significance of examining serum total bile acids(TBA) in diagnosis of cerrbral vascular diseases.Methods The sera TBA and blood lipid levels were measured in 29 cases of cerrbral infarction,26 cases cerrbral hemorrhage and 30 cases non cardiocerebral vasculer diseases by enzyme method.Results Compared with the cortrol group and cerrbral hemorrhage patients,the sera TBA levels were significantly higher in patients with cerebral infarction, (t=6.78,3.40,P<0.01). TBA levels in patients with cerrbral hemorrhage were also signifcantly higher than those in control group.(t=3.87,P<0.01).Conclusion Cerebral infarction and cerebral hemorrhage showed positive correlation with serum TBA level,so examining TBA level could be useful for the differential diagnosis between cerebral infarction and cerebral hemorrhage.