施他宁治疗重症急性胰腺炎的临床研究

Clinical Research of Stilamin in the Treatment of Acute Severe Pancreatitis

目的 评价施他宁治疗重症急性胰腺炎 (acuteseveritypancreatitis,SAP)的疗效。方法 采用施他宁治疗 2 5例SAP患者 ,进行临床多项指标和CT观察 ,并与传统方法治疗的 30例患者作比较。结果 施他宁能够显著降低血清淀粉酶和血LDH的水平 ,使SAP严重指数、并发症发生率和死亡率明显降低 ,与对照组相比差异有显著性 (P<0 .0 5 ) ;平均住院时间也明显缩短。结论 施他宁治疗SAP具有良好的效果。

Objective To evaluate the curative effect of stilamin in the treatment of severe acute pancreatitis(SAP).Methods The results of several clinical laboratory observations and computed tomography(CT) of 25 cases of SAP treated with stilamin was compared with those of 30 cases of SAP with classical treatment.Results The results showed that stilamin significantly decreased the levels of serum amylase and LDH,lowered the severity index and the occurrence of complications and the rate of mortality,it having significant differences from those In the control group,( P <0.05～ 0.01 ),and also shortened the duration of hospitalization.Conclusion It is concluded that stilamin has a good curative effect on SAP.