活体亲属供肾的肾移植5例报告

Living related donor renal transplantaion:A report of 5 cases

目的 探讨活体亲属供肾移植及术前特异性输供体血的安全性及可行性,并评价其临床效果。方法 总结5例活体亲属供肾移植的临床效果和供肾者术后的恢复情况。结果 5例活体亲属供肾者经随访10～24月全部健康,正常工作,术后无明显的并发症,5例肾移植受者目前移植肾功能(血肌酐及内生肌酐清除率)均正常,且已恢复正常的学习和工作,术后的免疫抑制剂使用量较同期的尸体肾移植受者低10％～15％。结论 活体亲属供肾是扩大供肾来源的较好途径,移植术后人/肾存活率优于尸体肾移植人/肾存活率。术前特异性输供体血有利于诱导受者产生免疫耐受。

Objective To investigate the safety and feasibility of living relaed dong kidney transplantation (LRKT) ,and evaluate the clinical effects of LRKT. Methods Retrospective analysis of 5 cases of kidney transplantation with living related donor from 1999- 2001 was carried out. Results The 5 living kidney donor were recovered successfully follow - up for 10 to 24 months, the living donor were health and working. The function of 5 renal transplantation including serum creatinine ratio(SCr) and Creatinine clearance ration(Ccr) was normal. 5 recipients had good quality of life,the doses of imunosuppresive drugs of living kidney recipients were less than that of cadaveric kidney recipients. Conclusion LRKT is safe and available. The living- related donor kidney transplantation is significantly better than cadaver kidney transplantation.