期刊文献+

骨髓间质干细胞研究进展 被引量:6

Research progress in bone marrow-derived mesenchymal stem cells
下载PDF
导出
摘要 Bone marrow stroma provides the microenvironment for hematopoiesis and is also the source of mesenchymal stem cells. Marrow mesenchymal stem cells are capable of self-renewal and differentiation into all mesodermal cell types and neuro-ectodermal cells, such as osteoblast, chondrocyte, myoblast, T/L fibroblast, stromal cell, adipocytes, neuron, astrocytes, and so on. These abilities make the mesenchymal stem cells as an excellent target cell of tissue engineering, cell transplantation and gene therapy. Bone marrow stroma provides the microenvironment for hematopoiesis and is also the source of mesenchymal stem cells. Marrow mesenchymal stem cells are capable of self-renewal and differentiation into all mesodermal cell types and neuro-ectodermal cells, such as osteoblast, chondrocyte, myoblast, T/L fibroblast, stromal cell, adipocytes, neuron, astrocytes, and so on. These abilities make the mesenchymal stem cells as an excellent target cell of tissue engineering, cell transplantation and gene therapy.
作者 项鹏 李树浓
出处 《中国病理生理杂志》 CAS CSCD 北大核心 2002年第11期1438-1442,共5页 Chinese Journal of Pathophysiology
基金 国家重点基础研究发展规划项目(973)(G1 9990 5430 0 )
  • 相关文献

参考文献1

二级参考文献9

  • 1[1]Johansson CB,Momma S,Clarke DL,et al.Identification of a neural stem cell in the adult mammalian central nervous system[J].Cell,1999,96(1): 25-34.
  • 2[2]Friedenstein AJ.Precursor cells of mechanocytes[J].Int Rev Cytol,1976,47: 327-355.
  • 3[3]Pittenger MF,Mackay AM,Jaiswal SC,et al.Multilineage potential of adult human mesenchymal stem cells[J].Science,1999,284(5411):143-147.
  • 4[4]Makino S,Fukuda K,Miyoshi S,et al.Cardiomyocytes can be generated from marrow stromal cells in vitro[J].J Clin Invest,1999,103(5): 697-705.
  • 5[5]Kopen GC,Prockop DJ,Phinney DG.Marrow stromal cells migrate throughout forebrain and cerebellum,and they differentiate into astrocytes after injection into neonatal mouse brains[J].Proc Natl Acad Sci USA,1999,96(19): 10711-10716.
  • 6[6]Digirolamo CM,Stokes D,Colter D,et al.Propagation and senescence of human marrow stromal cells in culture: a simple colony-forming assay identifies samples with the greastest potential to propagate and differentiate[J].Br J Haematol,1999,107: 275-281.
  • 7[7]Brazelton TR,Rossi FMV,Keshet GI,et al.From marrow to brain: expression of neuronal phenotypes in adult mice[J].Science,2000,290(5497): 1775-1779.
  • 8[8]Mezey E,Chandross KJ,Harta G,et al.Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow[J].Science,2000,290(5497): 1779-1782.
  • 9[9]Woodbury D,Schwarz EJ,Prockop DJ,et al.Adult rat and human bone marrow stromal cells differentiate into neurons[J].J Neurosci Res,2000,61(4): 364-370.

共引文献55

同被引文献59

引证文献6

二级引证文献34

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部