摘要
支气管哮喘急性发作,症状较重,经一般门诊常规治疗无效,持续24小时以上仍不能控制者为重症哮喘。本文就我所1980年1月～1983年8月间收治的重症哮喘51例进行小结、分析。一、临床资料(一)年龄与性别:男34例,女17例,男女之比为3∶1。年龄范围16～71岁,平均39.7岁,其中16～30岁9人(17.6%),31～50岁34人(66.6%),51～71岁8人(15.7%)。(二)诊断与诱因:本组病例有1～35年典型的支气管哮喘发作史,支气管解痉剂可使其缓解;本次入院时呈端坐抬肩,极度呼气性呼吸困难、表情焦虑或张口瞪目,困倦或烦躁或嗜睡,大汗淋漓,四肢较冷,脉搏细速。
The clinical data of 51 cases of severe asthma (34 male, 17 female, aged 16-71 years) were reported. Blood gas examination showed respiratory alkalosis in 26 cases, normal pH but with hypercapnea (PaCO_2>45mmHg) and hypoxemia (PaO_2<60mmHg) in 20 cases. Only 3 cases had respiratory acidosis combined with metabolic acidosis. Therefore, it is no need to give routine alkaline infusion in most of such patients, All patients were treated with aminophyllin, dexamethasone infusion, (and occassionally antibiotics)with a total fluid of 1000-2000ml/day. 24hrs' peak flow rate (PFR) was measured in 26 cases. 20 of them (76.2%) showed a dip of PFR from 0:00 to 6:00 Am. Authors suggested that infusion medication given just before sleep may have better bronchodilatation effect; Regular aerosol inhalation played an important role in relieving bronchospasm and promoting expectoration.
出处
《广东医学》
CAS
1984年第7期6-8,46,共4页
Guangdong Medical Journal
