摘要
为了构建二芳基醚的高效偶联反应,本文设计了一种大位阻的N-杂环卡宾钯催化剂用于催化C-O芳基化反应。论文探讨了以硝基苯衍生物为原料,N-杂环卡宾钯配体催化生成二芳基醚的研究。在优化反应条件的基础上,钯配合物C1能够在0.1mol%时高效合成一系列目标产物。
On the basis of development highly efficient protocol for Pd-catalyzed C-O cross-coupling reactions, bulky bis(imino)acenaphthene(BIAN)-supported NHC-Pd complexes was applied in the synthesis of diaryl ether. It is highlight that the iitrobenzene derivatives were selected as materials. It revealed that the bulky NHC-Pd complexe of C1 could be successfully employed in the coupling of aryl bromides at a low palladium loading of 0.1 mol %.
作者
张飞意
姚华刚
Zhang Feiyi;Yao Huagang(School of Chemistry and Chemical Engineering,Guangdong Pharmaceutical University,Zhongshan528458,China)
出处
《广东化工》
CAS
2019年第3期20-21,共2页
Guangdong Chemical Industry
关键词
硝基苯衍生物
二芳基醚
卡宾钯配合物
Nitrobenzene derivative
Diaryl ether
Carbene palladium complex