腹腔镜联合射频消融治疗多发肝腺瘤的诊疗体会

Clinical Experience in Treatment of Multiple Hepatic Adenomas using Laparoscopy and Radiofrequency Ablation

目的探讨腹腔镜联合射频消融微创化治疗多发肝腺瘤的可行性、安全性及其治疗效果。方法回顾性分析4例肝腺瘤患者的临床资料,并结合文献报道。结果 4例肝腺瘤患者中2例为多发肝腺瘤,男性患者3例,女性患者1例,中位年龄36.5岁,2例单发患者均给予行传统开腹肝腺瘤切除术,多发肝腺瘤患者均给予腹腔镜联合射频消融治疗,术后4例患者均痊愈出院,无并发症发生,经随访3~16个月,无复发。结论腹腔镜联合射频消融治疗多发肝腺瘤是安全有效可行的,不失为微创化治疗多发肝腺瘤的一个良好选择,但其长远疗效需进一步多中心、长期随访研究。

Objective To discuss and assess the feasibility,safety and outcomes of laparoscopy combined with radiofrequency ablation on treating multiple hepatic adenomas. Methods We retrospectively analyzed the clinical data of four cases of hepatic adenoma,and reviewed literature. Results Two were multiple hepatic adenomas in four cases of hepatic adenomas,three were male and one female,with median age of 36. 5 years. Two patients with single hepatic adenoma were treated with traditional open resection,the other patients with multiple hepatic adenomas were treated with laparoscopy and radiofrequency ablation. All patients were cured without complications,and there was no recurrence on follow-up which ranged from 3 to 16 months. Conclusions Laparoscopy combined with radiofrequency ablation is safe,effective and feasible on treating multiple hepatic adenomas. After all,it is a good choice for minimally invasive treatment of multiple hepatic adenomas,but its long-term effect needs further multi-center,long-term follow-up study.