云南两地区HCV抗体阳性者丙肝防治知识知晓率及诊疗现状

Awareness rate and status of diagnosis and treatment of hepatitis C among HCV antibody positives in two regions of Yunnan province

目的了解云南省两地区抗-HCV阳性者丙肝防治知识知晓率及诊疗现状,为丙肝患者诊疗措施的制定提供参考。方法采用方便抽样方法对云南省红河州和临沧市各医疗机构就诊者中通过被动筛查或主动检测发现的丙肝抗体阳性者进行调查,了解其实验室检测、转介、治疗等情况,采用SPSS 17. 0软件进行统计分析。结果共调查565例丙肝抗体阳性者,丙肝防治知识知晓率为45. 8%,文化程度越高知晓率越高,差异有统计学意义(χ~2=16. 455,P <0. 01);有吸毒史者知晓率高于无吸毒史者,差异有统计学意义(χ~2=31. 335,P <0. 01);两地区知晓率差异无统计学意义(χ~2=0. 888,P> 0. 05)。医疗机构丙肝诊疗服务提供率为71. 8%,转介率为79. 2%,成功转介率为13. 2%,核酸检测率为54. 2%,丙肝治疗率为19. 1%。结论云南省红河州和临沧市抗-HCV阳性者丙肝防治知识知晓率、成功转介率较低,治疗率有待提高,应继续加大丙肝防治知识宣传教育,提高公众丙肝防治意识,同时加强医务人员丙肝诊疗业务培训,提升其丙肝诊疗能力。

Objectives To understand the awareness rate and the status of diagnosis and treatment of hepatitis C among hepatitis C antibody positive patients,and provide the reference for the development of diagnosis and treatment of hepatitis C patients.Methods Convenient sampling was used for the questionnaire survey among hepatitis C antibody positives from medical institutions in Honghe and Lincang Prefecture of Yunnan province,and we understood their knowledge of hepatitis C and the hepatitis C detection,referral,treatment.SPSS 17.0 software was used for statistical analysis.Results Five hundred and sixty-five hepatitis C antibody positive patients were investigated in total,and the awareness rate of prevention and treatment of hepatitis C was 45.8%,the higher education level had the higher knowledge rate(χ~2=16.455,P<0.01);the awareness rate of who injected drugs was higher than who not injected(χ~2=31.335,P<0.01);and there was no statistically significant difference in awareness rates between the two places(χ~2=0.888,P>0.05).The rate of providing medical services was 71.8%,the referral rate was 79.2%,the successful referral rate was 13.2%,the detection rate of HCV-RNA was 54.2%,and the treatment rate of hepatitis was 19.1%.Conclusion Hepatitis C antibody positive patients in Honghe and Lincang prefecture have low HCV awareness and successful referral rate.Diagnosis and treatment rate need to be improved.Medical departments should continue to expend HCV awareness to improve public awareness of hepatitis C prevention and control,and strengthen medical staff training to improve their ability of hepatitis C diagnosis and treatment.