支气管肺泡灌洗液细菌定量培养在慢性支气管炎病原菌诊断上的应用

APPLICATION OF DIAGNOSING PATHOGENIC ORGANISMS IN CHRONIC BRONCHITIS BY QUANTITATIVE BACTERIAL CULTURES OF BRONCHOALVEOLAR LAVAGE FLUIDS

本文报导了34例次慢性支气管炎患者进行支气管肺泡灌洗液细菌定量培养结果,其中急性发作期20例、临床缓解期14例;还有10例对照组的结果。20例慢支急性发作期病人中,17例病人共培养出定量值≥1×10~5cfu/ml的致病菌25株,这些细菌浓度平均为10^(5.66±0.52)cfu/ml显著高于临床缓解期10^(3.19±0.81)cfu/ml(p<0.01)。和对照组10^(2.27±0.78)cfu/ml(p<0.01)。说明支气管肺泡灌洗液细菌定量培养法能较准确地分离出引起慢支急性发作的病原菌。

This paper reports the results of quantitative culture in 34 patient times with chronic brochitis, in which 20 patients were acute exacerbation status, 14 patients were clinical remission-stage. other 10 were control group.25 pathogenic organisms were recovered in concentrations≥lO^5 colony forming units (cfu) per milliliter in 17 of 20patients with acute exacerbation status. The average concentrations of these bacteria from acute exacerbation status (10^(5.66±0.52)cfu/ml) were significantly higher than that from remission stage (10^(3.19±0.81)cfu/ml) (p<0.01) as well as the control group (10^(2.27±0.78)cfu/ml) (p<0.01). Our results suggest that quantitative bacteria culture of bronchoalveoar lavage fluids can accurately seperated contaminant from patho genic organisms.