眼底血管病理改变特征提取方法研究进展

Advances in extraction methods of fundus pathological changes

眼底血管是活体能唯一观察到的人体终末血管,许多疾病在眼底血管的病理改变可通过多种手段进行观察,如检眼镜、眼底血管照相、激光共聚焦扫描眼底成像、荧光素眼底血管造影、光学相干断层扫描、多普眼底血管成像等,如何将观察到的病理改变准确提取,一直是学术界的难题,本文总结了眼底血管病理学改变的主要观察手段及病理改变的多种提取方法,包括眼底血管追踪法、像素分类法、匹配滤波法、阈值分割法等,并对眼底血管提取后的图像处理方法进行了总结,希望可以促进眼底血管病理特征提取方法的进一步发展,以利于临床疾病的诊断。

The fundus vessels are the only blood vessels that can be observed in the living body. The pathological changes of m any diseases in the fundus can be observed by various m eans, such as ophthalm oscopy, fundus angiography,laser confocal scanning fundus im aging,fluoresce in fundus angiography, optical coherence tom ography,Doppler fundus angiography,etc. Howto accurately extract the observed pathological changes has been a difficult problem in academ ia. This paper sum m arizes the m ain observation m ethods of pathological changes of fundus vessels and various extraction m ethods of pathological changes. Including fundus vascular tracking m ethod, pixel classification m ethod, m atching filtering m ethod, threshold segm entation m ethod, etc. And generalized the im age processing m ethods after fundus vascular extraction,hope to prom ote the further developm ent of fundus vascular pathological feature extraction m ethod,in order to facilitate diagnosis of clinical disease.