摘要
用 HPL C测定盐酸安非他酮中有关物质和降解产物 ,与主药有较好的分离效果。色谱柱为 Hypersil C1 8,流动相 0 .0 1m ol/ L磷酸二氢钾 (三乙胺调 p H7.0 ) -甲醇 (2 5∶ 75 ) ,检测波长 2 4 4 nm。
A RP-HPLC method for the determination of related substances and decomposition pro- ducts in bupropion hydrochloride was established. A Hypersil C_ 18 column was used with the mobile phase of 0.01 mol/L potassium dihydrogen phosphate (pH 7.0)-methanol (25∶75) at the detection wavelength of 244 nm.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2002年第12期608-609,共2页
Chinese Journal of Pharmaceuticals