妊娠期糖尿病患者平均血小板体积(MPV)和血小板平均分布宽度(PDW)与妊娠结局相关

Mean platelet volume(MPV) and mean platelet distribution width(PDW) in gestational diabetes mellitus patients were associated with pregnancy outcomes

目的:探究平均血小板体积(MPV)和血小板平均分布宽度(PDW)在妊娠期糖尿病患者的变化及对妊娠结局的影响。方法:150例妊娠期就诊患者分为妊娠期糖尿病组(52例)、妊娠糖耐量受损组(50例)、妊娠糖耐量正常组(48例),检测MPV和PDW。分析MPV、PDW与妊娠结局的相关性。结果:妊娠期糖尿病组患者的MPV、PDW高于其他两组,差异有统计学意义(P<0.05)。妊娠期糖尿病组Apgar 5 min评分低、低体重儿率、早产儿率等不良妊娠结局比其他两组差,差异有统计学意义(P<0.05)。MPV、PDW与不良新生儿围生期结局呈正相关。结论:MPV、PDW等血小板参数影响妊娠结局。

Objective:To explore the changes of mean platelet volume(MPV)and mean platelet distribution width(PDW)in gestational diabetes mellitus(GDM)patients and their effects on pregnancy outcomes.Methods:150 patients were divided into gestational diabetes mellitus group(52 cases),impaired gestational glucose tolerance group(50 cases),normal gestational glucose tolerance group(48 cases),MPV and PDW were detected.The correlation between MPV,PDW and pregnancy outcome was analyzed.Results:There were significantly high in MVP and PDW between gestational diabetes mellitus group and other two groups(P<0.05).Apgar 5-minute score,low birth weight rate and premature birth rate in gestational diabetes mellitus group were worse than those in other two groups(P<0.05).MPV and PDW were positively correlated with perinatal outcomes.Conclusion:MPV,PDW and other platelet parameters affect pregnancy outcomes.