丹参川芎注射液联合低分子肝素钙围手术期预防下肢深静脉血栓形成的临床观察

Clinical Observation on Salvia ChuanXiong Injection Combined With Low Molecular Weight Heparin Calcium in Preventing From Deep Vein Thrombosis of Lower Limbs During the Perioperative Period

目的评价丹参川芎注射液联合低分子肝素钙预防下肢血管围手术期深静脉血栓(DVT)形成的疗效。方法将50例62条下肢随机分成两组,A组31例于围手术期应用丹参川芎注射液10ml联合低分子肝素钙0.3~0.4ml,B组31例于围手术期只应用低分子肝素钙0.3~0.4ml。术后第4~7天常规行双下肢深静脉彩超检查,了解深静脉血栓发生情况。结果 A组无一例发生DVT,B组3例(9.6%)发生DVT,两组比较有显著差异('P<0.05')。结论丹参川芎注射液联合低分子肝素钙能有效预防下肢血管围手术期深静脉血栓形成。

Objective To evaluate effects of Salvia Chuanxiong injection combined with low molecular heparin calcium in preventing deep vein thrombosis( DVT) of lower limbs during the perioperative period. Methods 50 cases with 62 limbs were randomly divided into 2 groups. A group of 31 cases in perioperative were applied Salvia Chuanxiong injection 10ml and low molecular heparin calcium 0. 3 ~ 0. 4ml. Group B of 31 cases in perioperative were used only low molecular heparin calcium 0. 3 ~ 0. 4ml. Varicose veins color dopplar ultrasound of double limbs would be examined to understand the deep vein thrombosis after 4 ~ 7 days. Results No case in A group was happened DVT and 3 cases( 9. 6%) in B group occurred DVT,2 groups of comparisons had significantly difference( P < 0. 05). Conclusion Salvia Chuanxiong injection joint low molecular heparin calcium could effectively prevent the lower limbs perioperative blood vessels of deep vein thrombosis.