补泻同施、调节平衡法内外合治糖尿病下肢周围神经病变患者临床观察

Clinical Observation on Combined Internal-External Therapy of Reinforcing-Reducing and Adjusting the Balance in Treating Diabetic Lower Limb Peripheral Neuropathy

目的观察补泻同施、调节平衡法内外合治对糖尿病下肢周围神经病变患者TCSS评分、神经传导速度影响及临床疗效。方法将64例糖尿病下肢周围神经病变患者随机分为2组(每组32例),治疗组患者每天口服黄地吉仙汤并温通泡浴散浴足,补泻同施、调节平衡法内外合治;对照组患者每天口服甲钴胺片并温水浴足,12周后测定腓肠神经、腓总神经、胫神经传导速度、TCSS评分及临床有效率。结果 2组患者腓肠神经、腓总神经、胫神经传导速度、TCSS评分,治疗前后对比差异具有统计学(P <0. 05);治疗组腓肠神经、腓总神经、胫神经传导速度分别为(46. 48±3. 21)、(48. 68±4. 87)、(46. 65±2. 76) m/s,显著高于对照组的(40. 43±3. 24)、(42. 89±4. 05)、(41. 32±3. 53) m/s(P <0. 05);治疗组TCSS评分(8. 35±1. 15),显著低于对照组的(11. 12±1. 63)(P <0. 05);治疗组总有效率为71. 88%,显著高于对照组的59. 38%(P <0. 05)。结论补泻同施、调节平衡法内外合治,可以降低TCSS评分、增加神经传导速度、有效改善症状并提高临床疗效。

Objective To investigate the TCSS score,nerve conduction velocity and clinical curative effect with combined internal-external therapy of'reinforcing-reducing and adjusting the balance'on the diabetic lower limb peripheral neuropathy. Methods 64 cases of diabetic lower limb peripheral neuropathy were randomly divided into the treatment group and the control group. The treatment group was treated by oral Huangdi Jixian decoction on every day while bathing feet in Wentong Paoyu powder solution. The control group were treated by oral Mecobalamin on every day while bathing feet in warm water. The therapeutic effect was evaluated by measuring the conduction velocity of sural nerve,common peroneal nerve and tibial nerve,TCSS grade and the effective rate. Results Clinical symptoms amelioration were observed in two groups,however,the total effective rate( 71. 88%) in the treatment group were higher than that( 59. 38%) in the control group( P < 0. 05). Sural nerve conduction velocity( 46. 48 ± 3. 21 m/s),common peroneal nerve conduction velocity( 48. 68 ± 4. 87 m/s)and tibial nerve conduction velocity( 46. 65 ± 2. 76 m/s) in the treatment group were higher than Sural nerve conduction velocity( 40. 43 ±3. 24 m/s),common peroneal nerve conduction velocity( 42. 89 ± 4. 05 m/s) and tibial nerve conduction velocity( 41. 32 ± 3. 53 m/s) in the control group respectively( P < 0. 05). TCSS grade( 8. 35 ± 1. 15) in the treatment group were lower than that( 11. 12 ± 1. 63) in the control group( P < 0. 05). Conclusion Combined internal-external therapy of 'reinforcing-reducing and adjusting the balance'could effectively reduce TCSS score,increase nerve conduction velocity and improve clinical symptoms.