柴胡加龙骨牡蛎汤治疗肿瘤相关性失眠临床观察

Clinical Observation of Modified Chaihu Longgu Muli Decoction in the Treatment of Insomnia in Patients with Malignant Tumors

目的探讨柴胡加龙骨牡蛎汤用于肿瘤患者失眠治疗的有效性。方法纳入2018年7月—2018年11月肿瘤科接诊的失眠患者60例,采用随机分组,对照组采取中药加常规安眠药物治疗,治疗组则采取柴胡加龙骨牡蛎汤加减治疗。对比2组临床疗效、PSQI评分、睡眠质量评分。结果治疗组总有效率为90. 0%,高于对照组总有效率76. 7%。治疗后治疗组PSQI评分减少值大于对照组(P <0. 05);治疗后治疗组睡眠质量评分低于对照组(P <0. 05)。结论应用柴胡加龙骨牡蛎汤治疗肿瘤相关性失眠效果明确,值得临床推广。

Objective To explore the efficacy of Chaihu Longgu Muli decoction in the treatment of insomnia in cancer patients.Methods Sixty insomniacs admitted to our hospital from July 2018 to November 2018 were randomly divided into two groups.The control group was treated with traditional Chinese medicine and routine sleeping drugs,while the treatment group was treated with Chaihu Longgu Muli decoction.The clinical efficacy,PSQI score and sleep quality score of the two groups were compared.Result The total effective rate of the treatment group was 90.0%,higher than that of the control group 76.7%.After treatment,the PSQI score of the treatment group decreased more than that of the control group(P<0.05),and the sleep quality score of the treatment group was lower than that of the control group(P<0.05).Conclusion Chaihu Longgu Muli decoction is effective in the treatment of insomnia in cancer patients,which is worthy of clinical promotion.