自拟通阳汤联合常规治疗对急性脑梗死炎症反应的影响

Effect of Self-made Tongyang Decoction Combined with Conventional Therapy on Inflammatory Response in Patients with Acute Cerebral Infarction

目的探讨自拟通阳汤联合常规治疗对急性脑梗死患者炎症反应的影响。方法选取2018年1月—2019年1月在辽宁省沈阳市苏家屯区中西医结合医院内二科就诊的80例首发急性脑梗死患者,随机分为试验组和对照组,对照组40例采取降颅内压、抗凝、抗氧化和调脂等常规治疗方法,试验组40例在常规治疗方法的基础上给予自拟通阳汤。对比2组急性脑梗死患者治疗前后炎症因子的变化。结果治疗后试验组患者血清中的肿瘤坏死因子-α(TNF-α)及C反应蛋白(CRP)水平低于对照组患者,差异具有统计学意义(P <0. 05)。结论应用自拟通阳汤联合常规治疗急性脑梗死患者可使患者的炎症反应降低,值得在临床推广。

Objective To explore the effect of Tongyang decoction combined with routine treatment of inflammatory reaction in patients with acute cerebral infarction.Methods 80 patients with first-episode acute cerebral infarction treated in our department from January 2018 to January 2019 were selected.40 patients in the control group were treated with routine treatments such as lowering intracranial pressure,anticoagulation,antioxidation and lipid-lowering for patients with acute cerebral infarction.40 patients in the experimental group were treated with Tongyang decoction on the basis of routine treatment.Acute cerebral infarction patients,the changes of inflammatory factors in patients with acute cerebral infarction before and after treatment were compared between the two groups.Results After treatment,the levels of TNFalpha and CRP in patients with acute cerebral infarction in the experimental group were lower than those in the control group,and the difference was statistically significant(P<0.05).Conclusion The application of Tongyang decoction combined with routine treatment on acute cerebral infarction patients can reduce the inflammatory response,which is worthy of clinical promotion.