期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

细胞间粘附分子-1与慢性肝病 被引量：2

原文传递
导出
摘要 病毒感染、毒物及自身免疫等多种因素均可引起肝脏慢性炎症、损伤,进而发展为肝纤维化甚至肝硬化.然而,对于慢性肝病的病程监测及疗效评价,人们一直缺乏特异的非创伤性指标.近年来多项研究证实:细胞间粘附分子-1(ICAM-1)与肝脏的免疫及炎症反应存在密切联系,对观察病情进展,判断药物作用及估计预后都具有较高价值[1～5.8～15.17～20].
作者 潘勤 李定国
机构地区 上海第二医科大学附属新华医院
出处 《临床消化病杂志》 2002年第6期272-274,共3页 Chinese Journal of Clinical Gastroenterology
关键词 细胞间粘附分子-1 慢性肝病 生物学特性 炎症反应 免疫逃逸
分类号 R575 [医药卫生—消化系统]
  • 相关文献

参考文献10

  • 1Luna-Casado L,Diez-Ruiz A,Gutierrez-Gea F,et al.Increased periphera mononuclear cells expresion of adhension molecules in alcoholic cirrbosis: its relation to immune activation[].Journal of Hepatology.1997
  • 2Urbaschek R,Mccuskey RS,Rudi V,et al.Endotoxin, endotoxinneutralizing-capacity, sCD14, slCAM-1, and cytokines in patients with various degrees of alcohlic liver disease[].Alcoholism Clinical and Experimental Research.2001
  • 3Simpson KJ,Hayes PC.Soluble adhension molecules in immune mediated liver disease[].Gut.1995
  • 4Bloom S,Fleming K,Chapman R.Adhension inolecule expression in primary selerosing cholangitis and primary biliary cirrhosis[].Gut.1995
  • 5David A,Elizabeth M,Patrizia B,et al.Detection of circulating intercelluar adhension moleeule-1 in chronic liver diseares[].Hepatology.1992
  • 6David A,Stefan H,Jcan S,et al.Increased expression of intercellular adhension molecule l on bile ducts in primary biliary cirrhosis and primary sclerosing cholangitis[].Hepatology.1991
  • 7Thomson AW,Satoh S,Nussler AK,et al.Circulating intercellular adhension molecule-1 (ICAM-1) in autoimmune liver disease and evidence for the production of ICAM-1 by cytokine-stimulated humanhepatocytes[].Clinical and Experimental Immunology.1994
  • 8Nouri-Aria K,Koskinas J,Tibbs CJ,et al.Serum intercellular adhenssion molecule-l levels in chronic hepatitis C: association with disease activity and response to interferon alpha[].Gut.1995
  • 9Spahr L,Rubbia-Brandt L,Pugin J,et al.Rapid changes in Alcoholic hepatitis histology under steroids: correlation with soluble intercellular adhension molecule-l in hepatic veous blood[].Journal of Hepatology.2001
  • 10Claus H,Saixi CW,Hidekazu T,et al.Ezpression of intercellular adhension molecule I by activated hepatic stellate cells[].Hepatology.1996

同被引文献22

  • 1牟兆新,侯振江.CD_(44)及其在肿瘤研究中的进展[J].医学综述,2006,12(6):341-343. 被引量：7
  • 2吴孟超.肝癌外科治疗的近期进展[J].中国普外基础与临床杂志,2006,13(2):125-128. 被引量：71
  • 3刘岑,金伯泉.黏附分子[A].见:金伯泉主编.细胞和分子免疫学[M].第1版.西安:世界图书出版公司,1995:33-66
  • 4Lum AF, Green CE, Lee GR, et al. Dynamic regulation of LFA-1 activation and neutrophil arrest on intercellular adhesion molecule 1 (ICAM-1) in shear flow [J]. J Biol Chem, 2002; 277(23) : 20660
  • 5Green CE, Schaff UY, Sarantos MR, etal. Dynamic shifts in LFA-1 affinity regulate neutrophil rolling, arrest, and transmigration on inflamed endothelium [J]. Blood, 2006; 107(5) : 2101
  • 6王燕 周力 李利.原发性肝癌sICAM-1,sP-selectin检测及意义.中华医学研究杂志,2004,4(5):185-185.
  • 7Porgador A, Mandelboim O, Restifo NP, et al. Natural killer cell lines kill autologous beta2-microglobulin-deficient melanoma cells: implications for cancer immunotherapy [J]. Proc Natl Acad Sci USA, 1997, 94(24):13140
  • 8Luna EJ, Hitt AL. Cytoskeleton-plasma membrane interactions [J]. Science, 1992, 258(5084) :955
  • 9庄庆琪.细胞骨架[A].见:陈惠黎主编.生物大分子的结构和功能[M].第1版.上海:上海医科大学出版社,1999:143-166
  • 10Cunningham CC. Actin structural proteins in cell motility[J]. Cancer Metastasis Rev, 1992 ,11 (1):69

引证文献2

二级引证文献2

临床消化病杂志
2002年 第6期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部