纤维素硫酸酯制备研究进展

Research progress in preparation of cellulose sulfate

纤维素硫酸酯是一种具有独特生物学性质的纤维素衍生物,由于其具有抑菌、抗病毒及抗凝血等功效,并且具有良好的生物降解性和生物相容性,无毒无害、绿色环保,所以在食品、医药、化工等领域有着广泛的应用前景。但是目前纤维素硫酸酯还未被用于商品化,其制备方法尚处于研究开发阶段。目前纤维素硫酸酯的制备方法主要分为3类,分别是均相制备法、非均相制备法及准均相制备法。总结归纳了纤维素硫酸酯的制备方法,并介绍分析了各种制备方法各自的特点,为制备取代度、分子量等性质可控的纤维素硫酸酯提供理论依据。

Cellulose sulfate is a cellulose derivative with unique biological properties.Due to its antibacterial,antiviral and anticoagulant effects,it has good biodegradability and biocompatibility,and is non-toxic and environmentally friendly.Therefore,it has broad application prospects in the fields of food,medicine and chemical industry.However,cellulose sulfate has not been used commercially yet,and its preparation method is still in the research and development stage.At present,the preparation methods of cellulose sulfate are mainly divided into three categories.They are homogeneous preparation method,heterogeneous preparation method and quasi-homogeneous preparation method.In this paper,the preparation methods of cellulose sulfate were summarized,and the characteristics of each preparation method were analyzed.It provided a theoretical basis for the preparation of cellulose sulfates with controlled properties such as degree of substitution and molecular weight.