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Relationship between elderly dementia and plasma homocysteine level

Relationship between elderly dementia and plasma homocysteine level
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摘要 Objective To investigate relationship between elderly dementia and plasma homocysteine level.Method 69 patients with elderly dementia(ED) and 69 heathy seniles were selected and their plasma homocysteine (Hcy)level was determined by high performance liquid chromatography and fluorescene detector.Result Plasma Hcy level in study was (26.5±11.8)μmol/L while in control group it was (12.4±2.4) μmol/L,(P< 0.001). Conclusion Higher plasma Hcy level could be a risk factor to the onset of ED. Objective To investigate relationship between elderly dementia and plasma homocysteine level.Method 69 patients with elderly dementia(ED) and 69 heathy seniles were selected and their plasma homocysteine (Hcy)level was determined by high performance liquid chromatography and fluorescene detector.Result Plasma Hcy level in study was (26.5±11.8)μmol/L while in control group it was (12.4±2.4) μmol/L,(P< 0.001). Conclusion Higher plasma Hcy level could be a risk factor to the onset of ED.
出处 《中国临床康复》 CSCD 2002年第23期3615-3615,共1页 Chinese Journal of Clinical Rehabilitation
关键词 血浆 月型半胱氨酸 老年期痴呆 临床意义 homocysteine elderly dementia high performance liquid chromatography fluorescence detector.
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参考文献2

  • 1EVERS,KOCHHG,GROTEROTEMEYERKH,etal.Features,symptomsandneurophysiologicalfindingsinstrokeassociatedwithhyperhomoc-ysteinemia犤J犦[].Archives of Neurology.1997
  • 2SESHADRIS,BEISERA,SELHUBJ,etal.PlasmaHomocysteineasariskfactorfordementiaandAlzheimer’sdisese犤J犦. The New England Journal of Medicine . 2002

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