摘要
目的 :研究腹腔镜手术前后周围静脉血红细胞第 1补体受体 (CR1)免疫粘附活性 ,腹腔内的pH值及红细胞CR1免疫粘附活性的改变。方法 :抽取周围静脉防凝新鲜血 2ml测定红细胞CR1免疫粘附活性。术后 12h再次抽取周围静脉血检测上述指标变化。手术中留取腹腔血性渗液测定红细胞CR1免疫粘附活性及腹腔液pH值 ,并与术中测定的周围血相应值比较。结果 :腹腔镜手术后红细胞CR1免疫粘附活性明显降低 ,腹腔液pH值在腹腔镜手术结束时明显下降 ,腹腔内的红细胞CR1免疫粘附活性明显降低。结论 :腹腔镜手术中CO2 气腹造成腹腔内pH值明显下降 ,红细胞CR1免疫粘附活性明显降低 ,可能是造成腹腔镜术中炎症扩散的原因之一。
Objective:To study the changes of immunoadhesion function of RBC CR 1 in peripheral veins before and after laparoscopic operation, changes of pH value, and the immunoadhesion function of RBC CR 1 in abdominal cavity.Methods:The immunoadhesion of RBC of fresh blood of peripheral vein were assayed at 30 minutes before operation, and 12 hours after operation. And the intraoperational immunoadhesion of RBC CR 1 and pH value in abdominal cavity were assayed and compared with the indexes of peripheral vein blood. Results:The immunoadhesion of RBC in peripheral vein blood decreased obviously after laparoscopic operation. Immunoadhesion of RBC and pH value in abdominal cavity decreased at the end of operation.Conclusions:Because of the influence of CO 2 pneumoperitoneum on the pH value in abdominal cavity, the immunologic function in peripheral vein blood and abdominal cavity attenuate. Which may be one of the reasons of proliferation of inflammation.
出处
《腹腔镜外科杂志》
2002年第4期198-200,共3页
Journal of Laparoscopic Surgery
