新型填充柱-表面增强拉曼光谱联用法的建立及应用

Establishment and Application of Novel Packed Column-Surface-Enhanced Raman Spectroscopy Method

基于有机骨架材料超高比表面积及优越的吸附性能,建立新型填充柱-表面增强拉曼光谱联用法。采用金属有机骨架复合材料联合常规色谱硅胶制备一种具有增强拉曼信号功能的增强新型填充柱,然后采用原位检测的方式,将其应用于鉴别中药材是否染色掺伪。采用上述方法,成功检测出经2种常见染料(新品红、胭脂红)染色的西红花药材。结果表明,搭建的新型填充柱-表面增强拉曼光谱联用法可对染色的中药材实现简单、快速、灵敏的检测,具有非常广阔的应用前景。

The method of novel packed column modified by metal organic frameworks combing with surface-enhanced Raman spectroscopy was established based on the high specific surface area and excellent adsorption properties of metal organic frameworks.A novel packed column with enhanced Raman signal function was prepared by metal organic frameworks combined with conventional chromatography silica gel.Then,in-situ detection was used to identify the adulteration of Chinese medicinal materials.Two dyes in dyed Croci Stigma were successfully detected by established method.The results show that the method of novel packed column-surface-enhanced Raman spectroscopy can be used to detect the dyed Chinese materials.In addition,the method has been proved to be simple,fast and sensitive,and has a wide application prospects.