太赫兹波段超材料在生物传感器的应用研究进展

Research Progress in the Application of Biosensors by Using Metamaterial in Terahertz Wave

超材料对电磁场的局域增强以及对周围环境的介电性质敏感等特性,可用于无标记生物检测,因而越来越受到国内外的学术关注,特别是太赫兹波段的超材料生物传感器。总结了近年来太赫兹波段超材料在生物传感器方面取得的进展。首先介绍了超材料生物传感器的基本原理,接着分析和讨论了衬底材料和厚度的选择、超材料结构对传感器灵敏度的影响。分析表明,通过优化结构、采用低介电常数和损耗低的薄衬底,能进一步提高生物传感器的灵敏度,并且多种物质在太赫兹波段都有直接的电磁响应特征,因此利用太赫兹波段超材料实现无标记生物检测具有很大的应用潜力。最后初步探讨了该生物传感器的发展趋势与前景。

In the present paper,the recent progress in terahertz metamaterials-based sensing is reviewed with the principle of metamaterial biosensor,metamaterial substrate,and structure design,respectively.The paper introduces the principle in detail,analyzes the sensitivity of the biosensor with the material and the thickness of the substrate and the structure of metamaterial.The analysis shows that we can enhance the sensitivity and resolution of biosensor by designing specific metamaterial structure,using low dielectric constant and low loss thin substrate,especially many materials have a specific response in the terahertz frequency.So,there is a large potential application for label-free sensing by using the terahertz metamaterials.This paper also presents the future development of THz metamaterial sensors.