溶液中石墨烯界面上Aβ(37-42)振动光谱研究

The Vibrational Spectra of Aβ(37-42)on Ggraphene in Solution

开展分子动力学模拟,探究溶液中石墨烯界面上Aβ(37-42)片段的动态结构及其表现的振动光谱特征。借助Aβ骨架上酰胺-A带吸收光谱表征其结构变化,为探究石墨烯对Aβ折叠机制的影响提供有力的理论支持。

The dynamical structure and corresponding vibrational spectra of Aβ(37-42)on graphene in aqueous solution were investigated through molecular dynamic simulation.The structural feature was characterized via the adsorption spectra of amide-A bands of Aβbackbone.It provided theoretical insight for the impact of graphene on the folding mechanism of Aβprotien.