苏黄止咳胶囊联合复方甲氧那明胶囊治疗感染后咳嗽的临床观察

Clinical observation on Suhuang Zhike capsule combined with compound methoxyphenamine capsule for the patients with post-infectious cough

目的观察苏黄止咳胶囊联合复方甲氧那明胶囊治疗感染后咳嗽的临床疗效及安全性。方法 100例感染后咳嗽患者随机分为治疗组和对照组(各50例),治疗组采用苏黄止咳胶囊联合复方甲氧那明胶囊,对照组仅采用复方甲氧那明胶囊,治疗结束后比较两组患者的咳嗽症状评分、呼出气一氧化氮浓度及临床控显率。结果治疗1周后,治疗组咳嗽症状评分低于对照组,控显率(98.0%)高于对照组(84.0%),差异均具有统计学意义(P<0.05)。治疗组不良反应的发生例数较对照组无明显增加。结论苏黄止咳胶囊联合复方甲氧那明胶囊治疗感染后咳嗽疗效显著,见效快,未发现明显不良反应,值得临床推广应用。

Objective To observe the clinical efficacy and safety of Suhuang Zhike capsule combined with compound methoxyphenamine capsule in treating post-infectious cough(PIC). Methods One hundred patients with PIC were randomly divided into treatment group and control group with 50 cases each. The treatment group was given Suhuang Zhike capsule and compound methoxyphenamine capsule, and the control group was only given compound methoxyphenamine capsule. Cough score, exhaled nitric oxide level and the total effective rate after one week treatment in both two groups were compared. Results Cough score in treatment group were lower significantly than that in control group. The total effective rate of treatment group and control group were 98.0% and 84.0% respectively. The differences between two groups were statistically significant(P< 0.05). Adverse effect rate was similar between the two groups. Conclusion Suhuang Zhike capsule combined with compound methoxyphenamine capsule are effective for PIC. No adverse or toxic effect is shown during clinical observation.