摘要
目的观察胃癌患者手术前后的中医证候及变化情况,探索胃癌患者围手术期中医证候演变规律。方法以2015年6月至2016年1月第二军医大学附属长海医院中医系康复医学科胃癌手术后的患者为研究对象。对胃癌术后患者进行中医证候调查,将证型分为气虚证、血虚证等十个证型。结果共纳入病例105例,发现术前中医证候以气滞证、血瘀证等实证(43.81%)为主,术后初期(术后第1 d)中医证候以虚证为主(99.05%),尤以气虚证患者最多(91.89%),术后中期(第3~5 d)中医证候最为多见的是气虚证97例(64.66%)和寒湿证35例(23.33%),术后后期(第7~10 d)中医证候以虚实夹杂证为主(51.43%),其中以气虚证95例(59.01%),寒湿证52例(32.30%)为主,与术前比较差异有统计学意义(P<0.05)。结论胃癌围手术期中医证候演变规律为"由实转虚,虚证为本,虚实夹杂",以气虚证和气虚证+寒湿证最为多见。
Objective To investigate the evolution rule of traditional Chinese medicine(TCM) syndromes of patients with gastric cancer during perioperative period. Methods A total of 105 patients with gastric cancer, who received surgery in the Changhai Hospital of Second Military Medical University from June 2015 to January 2016, were selected and enrolled as the subjects. The TCM syndromes of gastric cancer patients after operation were investigated. Results Before surgery, the TCM syndromes of patients were mainly Qi stagnation syndrome and blood stasis syndrome(43.81%). In the early postoperative period, the TCM syndrome was mainly caused by deficiency syndrome(99.05%) especially Qi deficiency syndrome(91.89%). After the mid period the TCM syndromes were Qi deficiency syndrome in 97 cases(64.66%) and cold dampness syndrome in 35 cases(23.33%). After the late period the TCM syndrome was syndrome of intermingled deficiency and excess(51.43%), and among them 95 cases of Qi deficiency syndrome(59.01%) and 52 cases of cold dampness syndrome(32.30%). Conclusion TCM syndromes of gastric cancer patients during perioperation period are changed. In most common cases the TCM syndromes are Qi deficiency syndrome and the Qi deficiency plus cold dampness syndrome.
出处
《世界临床药物》
CAS
2017年第12期826-829,846,共5页
World Clinical Drug
基金
上海市进一步加快中医药事业发展三年行动计划建设项目(编号:ZY3-CCCX-3-7002)
关键词
胃癌
围手术期
中医证候
演变规律
gastric cancer
perioperative period
traditional Chinese medicine syndrome
evolution rule