肾性高血压的诊治新进展

Progress in diagnosis and treatment of renal hypertension

肾脏是调节血压的重要器官,肾脏实质性病变和肾动脉病变引起血压升高称为肾性高血压。高血压可发生在肾脏疾病的任一阶段,高血压可加剧肾脏病变引起肾功能减退,形成恶性循环,从而导致肾脏病患者的高致残率和死亡率。肾性高血压不仅有高血压本身的危害外,还可伴随电解质紊乱和内分泌失衡等独立于血压之外的损害。因此早发现、早诊断和早治疗肾性高血压显得尤为重要。肾性高血压的发病机制、临床表现和治疗与普通高血压人群有所差异,需要给予特别关注和专门研究。本文主要对肾性高血压的定义、发病机制及治疗方法作简要综述,以供临床参考。

Kidney is an important organ to regulate blood pressure.Renal hypertension is caused by renal substantial lesions and renal artery lesions.Hypertension can occur in any stage of kidney disease.Hypertension exacerbates kidney disease and also causes renal dysfunction,and can form a vicious cycle that leads to high disability rate and death rate in patients with kidney disease.Renal hypertension not only has the harm of hypertension itself,but also can be accompanied by electrolyte disorder,endocrine imbalance and other independent damages from high blood pressure.Therefore,early detection and diagnosis,and early treatment of renal hypertension are particularly important.The pathogenesis,clinical manifestations and treatment of renal hypertension are different from the general hypertension population,which needs special attention and special researches.This article mainly summarizes the definition,pathogenesis and treatment of renal hypertension for clinical reference.