男性雄激素的生理基础及其检测进展

Physiologic basis of male androgen and recent progress in their measurement

雄激素是与男性性功能及生殖均密切相关的性激素。准确检测雄激素对男科临床工作意义重大。目前国内检测雄激素的方法仍以化学发光法为主,质谱技术尚未普及,而对游离睾酮的检验在临床上也较为少见,这也限制了相关疾病诊疗水平的发展。本文对雄激素的生理基础及临床现有检测方法的进展作一综述。

Androgen is an important sexual hormone related to male sexual function and reproduction.Accurate testing method for androgen is important for the clinical practice of andrology.Until now,chemiluminescence is the general method used for testing androgen in our country.Mass spectrometry has not been popularly used.And the free testosterone test is also seldom used in clinical practice.This situation limit the development of the diagnosis and therapy of related diseases.This article reviews the physiology and the progress of current clinical development of measurement technique of androgen.