64层螺旋CT血管成像对颈动脉分叉处病变的临床应用

The clinical application of 64-slice spiral CT angiography in carotid artery bifurcation disease

目的探讨64层螺旋CT血管成像(CTA)在诊断颈内动脉狭窄和粥样硬化斑块中的价值,并与当前血管成像的金标准DSA进行比较。方法对40例病人(80个颈动脉)进行了CTA和DSA检查,两项检查时间间隔不超过1周,并将CTA与DSA结果进行对照,计算出两者之间的敏感度和特异度。结果CTA对轻度(狭窄程度:0～29%)颈动脉狭窄和颈动脉闭塞显示得非常好,其敏感度和特异度均接近100%。在明确经DSA测量狭窄程度】50%的狭窄时,CTA敏感度、特异度分别为89%、91%。CTA在鉴别狭窄程度为50%～69%或70%～99%时的特异度高,而敏感度较低,分别为65%和73%。CTA同时可以检出DSA不能发现的所有类型的斑块。结论64层CTA在显示颈内动脉狭窄方面与DSA有很好的一致性,同时可发现与颈动脉狭窄相关的溃疡,而DSA只能显示狭窄。

Objective To explore the clinical value of 64-slice spiral CT angiography(CTA) in carotid stenosis and atherosclerotic plaque. Methods 40 patients (80 carotid arteries) underwent CTA and DSA. These two examinations within one week. The results of CTA were compared with that of DSA,the sensitivity and specificity of CTA and DSA were figured out. Results CTA performed well in the detection of mild (0% to 29%) carotid stenosis, as well as carotid occlusion, with values for sensitivity and specificity both near 100%. In determining that a stenosis was>50% by DSA measurement, CTA with a sensitivity, specificity of 89% and 91% respectively. While CTA was quite specific in identifying degrees of stenoses in either the 50% to 69% or the 70% to 99% ranges, in this task it was much less sensitive: 65% and 73% respectively. CTA can detect all kinds of ulcers while DSA can not. Conclusions 64-slice CTA and DSA were correctly identified in detecting carotid stenosis. CTA could demonstrate ulcers associated with the carotid stenosis, but DSA only show stenosis.