血常规和超敏C反应蛋白检测结果在毒蛇咬伤治疗前后的变化规律

Change regulation before and after treatment of snake bite for routine blood test and hypersensitive C-reactive protein

目的探讨各种毒蛇咬伤患者治疗前后血常规和血清超敏C反应蛋白(hs-CRP)的变化规律。方法选择近2年住院治疗、属于何种蛇伤诊断明确的毒蛇咬伤患者作为研究对象,这些患者在治疗前后均进行血常规和血清hs-CRP检测,按蛇种、时段及病情对检测结果作出统计分析。结果治疗前仅蝰蛇咬伤患者WBC明显升高,治疗后第1、2天5种毒蛇咬伤患者WBC均显著升高(P<0.01),治疗后第4天该指标均有下降趋势,但检测值仍高于正常参考范围。治疗前后5种毒蛇咬伤患者RBC和HGB均在正常水平,没有明显变化。竹叶青蛇咬伤患者在治疗前、蝰蛇咬伤患者在治疗前后出现血小板(PLT)减少(P<0.05)。hs-CRP水平治疗前以蝰蛇咬伤患者较高、治疗后以眼镜蛇咬伤患者最高,差异有统计学意义(P<0.05)。结论 5种毒蛇咬伤患者治疗前后基本上无贫血症状,但大多数患者出现炎症反应,竹叶青蛇、特别是蝰蛇咬伤患者PLT减少比较严重。

Objective To probe into the change regulation before and after treatment every snake bite patients for the routine blood test and serum hs‐CRP .Methods The study objects were selected in the hospitalized patients for clear diagnosis belong to what kind of snakes in the past two years .The indexes of routine blood test and serum hs‐CRP were determined before and after treatment various periods in these patients .The test results were made to statistical analysis according to kind of snakes ,periods and disease condition .Results WBC was obvious .rise before treatment only the viper snake bite patients .WBC was all significant .rise after treatment first day and second day for 5 kinds snake bite patients (P<0 .01) .This index had all reduced trend after treatment fourth day but determined value was still high in contrast to the normal reference scope .RBC and HGB all were normal level and had not obvious change before and after treatment for 5 kinds snake bite patients .PLT was reduced before treatment for the trime‐resurus gramineus bite patients ,before and after treatment for the viper snake bite patients (P<0 .05) .The hs‐CRP content was higher before treatment for the viper snake bite patients and was highest after treatment for the cobra snake bite patients ,the inter‐comparison had significant difference (P<0 .05) .Conclusion 5 kinds snake bite patients before and after treatment not basely ane‐mia symptom .But most of the patients appear the inflammatory response .PLT decrease is more serious for the trimeresurus grami‐neus bite patients ,and for the viper snake bite patients especially .