儿童血细胞减少血液疾病的临床分析

Clinical analysis of the hemocytopenia blood diseases in children

目的回顾分析血细胞减少的血液疾病患儿的临床及实验室特点,了解血细胞减少与疾病关系,以提高对相关疾病的认识,提高诊疗水平。方法对217例血细胞减少的血液疾病患儿1系、2系、3系减少者分别进行分析,探讨其贫血程度与常见疾病关系。结果 185例血细胞减少病例分析中,1系降低主要见于特发性血小板减少性紫癜(37.2%)、血小板减少性症(19.8%)、粒少或粒缺(9.1%);2系降低主要见于急性白血病(43.6%)、特发性血小板减少性紫癜(21.7%)和再生障碍性贫血(6.5%);3系降低主要见于急性白血病(38.9%)和再生障碍性贫血(33.6%);180例血细胞减少患儿中常见引起贫血的疾病分别是急性白血病(20.0%)、特发性血小板减少性紫癜(19.4%)和无临床诊断的贫血类型(16.1%)。结论通过对217例血细胞减少的血液疾病患儿的临床及实验室特点进行分析,提高了临床上血液疾病的相关认识,也对相应血液疾病的实验室数据、比例有所了解。

Objective To review the clinical and laboratory characteristics of the hemohemocytopenia diseases in children,in order to improve the understanding of the related diseases and the level of diagnosis and treatment.Methods A total of 217 children with hemocytopenia diseases with one,two or three series of cell reducing,and the degree of blood cells reduce with anemia and common diseases in children.Results In 185 cases with the hemocytopenia diseases,1 series reduce were mainly in idiopathic thrombocytopenic purpura(ITP,37.2%)、thrombocytopenia(19.8%),granulocytopenia or agranulocytosis(9.1%).2series reduces mainly in acute leukemia(43.6%),the ITP(21.7%)and aplastic anemia(6.5%).3 series reduce mainly in acute leukemia(38.9%)and aplastic anemia(33.6%).Common cause of anemia in children with 180 cases of hemohemocytopenia diseases were acute leukemia(20.0%),the ITP(19.4%)and no clinical diagnosis of anemia(16.1%).Conclusion After analyzing the characteristics of the patient′s clinical and laboratory in 217 cases of hemocytopenia diseases,improve the clinical blood disease related knowledge,help understand the laboratory data and proportion.