应用降糖通脉胶囊联合运动锻炼可改善老年肥指标和抑郁情绪

The Application of Jiangtang Tongmai Capsule Combined with Exercise Could Improve the Index of Obesity and Depression

为了探讨降糖通脉胶囊联合运动锻炼对老年肥胖患者肥胖指标、抑郁情绪的影响,本研究选取了2015年1月至2016年10月我院120例老年肥胖患者,随机分为观察组和对照组,各60例,对照组在接受西医常规治疗基础上进行同步运动锻炼,观察组加用降糖通脉胶囊治疗,疗程均为14 d。观察2组临床疗效、肥胖指标、空腹血糖(FBG)、餐后2 h血糖(2hPG)及糖化血红蛋白(HbAlc),比较两组患者治疗前后生活质量、抑郁评分。研究发现,治疗组总有效率为96.7%(58/60),对照组为83.8%(50/60),两组比较差异有统计学意义(χ2=11.23, p<0.01);观察组BMI、WHR、腹围及股围显著低于对照组,差异有统计学意义(p<0.01);治疗后,观察组躯体功能((59.15±9.51)比(55.12±4.36), t=7.03)、心理功能((72.25±3.18)比(65.08±5.31),t=8.36)、社会功能((70.14±8.57)比(68.00±6.46), t=6.38)评分高于对照组(p <0.05);治疗后FBG ((6.5±1.4)mmol/L比(8.2±1.7) mmol/L, t=8.05)、2hPG ((8.6±2.1) mmol/L比(11.3±2.5) mmol/L, t=7.84)、HbAlc ((5.1±1.0)%比(6.4±1.5)%, t=6.38)水平低于对照组(p<0.05);治疗后观察组HAMA ((9.35±2.21)比(11.43±2.08), t=7.31)、HAMD评分((9.09±2.38)比(11.53±3.31), t=8.35)低于对照组(p<0.05)。研究表明,降糖通脉胶囊联合运动锻炼治疗老年肥胖患者效果显著,能有效降糖降脂,降低肥胖指标,改善生活质量及抑郁情绪,值得推广。

In order to explore the effects of Jiangtang Tongmai capsules combined exercise on obesity indicators and depression mood in elderly ob ese patients,in this study,120 elderly obese patients in our hospital were selected from January 2015 to October 2016,and were randomly divided into observation group and control group,with 60 patients in each group.On the basis of conventional western medicine treatment,the control group was treated with synchronous exercise,while the observation group was treated with jiangtang tongmai capsule,and the course of two groups was both 14 days.The clinical efficacy,obesity index,fasting blood glucose,2 hPG and HbAlc were observed in two groups,and depression score and quality of life were measured in two groups of patients.The study found that the total effective rate of the treatment group was 96.7%(58/60),and that of the control group was 83.8%(50/60).The difference between the two groups was statistically significant(x2=11.23,p<0.01).The BMI,WHR,waist and thigh circumference of the observation group was significantly lower than that of the control group,and the difference was statistically significant(p<0.01).After treatment,the physical function((59.15±9.51)vs(55.12±4.36),t=7.03),psychological function((72.25±3.18)vs(65.08±5.31),t=8.36),social function scores((70.14±8.57)vs(68.00±6.46),t=6.38)of the observation group was higher than that of the control group(p<0.05);The FBG((6.5±1.4)mmol/L vs(8.2±1.7)mmol/L,t=8.05),2 hPG((8.6±2.1)mmol/L vs(11.3±2.5)mmol/L,t=7.84),HbAlc((5.1±1.0)%vs(6.4±1.5)%,t=6.38)level of observation group was lower than that of the control group(p<0.05);The HAMA((9.35±2.21)vs(11.43±2.08),t=7.31),HAMD((9.09±2.38)vs(11.53±3.31),t=8.35)score of the observation group was lower than that of the control group(p<0.05).The study indicated that Jiangtang Tongmai capsules combined with exercise training had significant effect on the treatment of elderly obesity patients,which could effectively reduce blood sugar and lipid,reduce obesity index,improve the quality of life and depression,and would be worthy of promotion.