老年缺血性脑血管病与颈动脉粥样硬化的相关性研究

Correlation of the aged ischemic cerebral infarction with carotid artery atherosclerosis

目的 探讨老年缺血性脑血管病 (ICD)与颈动脉粥样硬化的相关性。方法 依有无临床症状及头颅CT或MRI检查结果 ,将 85例老龄患者分为 3组 :非梗死组 (NI组 )、无症状性脑梗死组 (AI组 )和症状性脑梗死组(SI组 ) ,各组病人均行颈部血管彩色多普勒显像检查。结果 SI组和AI组斑块指数增高、颈动脉内 -中膜厚度(IMT)增加、颈内动脉 (CIA)及颈总动脉 (CCA)内径均较低 ,与NI组相比有统计学意义 ;SI组斑块指数、IMT较AI组亦有显著增高。结论 ICD与颈动脉粥样硬化密切相关 ,颈动脉粥样硬化可作为预测及评价ICD的重要指标之一。

Objective To study the relation ship of the aged ischemic cerebral disease (ICD) with carotid artery atherosclerosis. Methods Based on clinical manifestations and the result of brain CT or MRI, 85 elderly patients were divided into three groups: no infarction group(NI group)? asymptomatic infarction group(AI group) and symptomatic infarction group(SI group). The relation of ICD with the carotid artery atherosclerosis was assessed by color-Doppler in the three groups. Results Compared with NI group, the plaque score and intimal-medial thickness (IMT) of carotid artery were significantly higher, and as a result, the lumen diameter of carotid internal artery (CIA) and common carotid artery (CCA) were lower in SI group and AI group. These differences could also be found between SI group and AI group. Conclusion Ischemic cerebral infarction is closely related with carotid artery atherosclerosis. The presence or absenec of atherosclerosis of carotid artery may be an important index in evaluation of ischemic cerebral infarction of aged patients.