睡眠质量与中青年原发性高血压发病的横断面研究

Correlation between sleep quality and occurrence of primary hypertension in young and middle-aged population: A cross-sectional study

目的:以洛浦社区45岁以下中青年作为研究人群,通过横断面研究,对其血压及睡眠质量的关联性进行分析。方法:通过PHQ-9调查问卷、匹茨堡睡眠质量指数量表,对招募患者的抑郁情况、睡眠质量进行调查,通过binary logistics回归,观察睡眠质量回归系数效应值的变化。结果:变量体重指数、尿酸、甘油三酯、谷丙转氨酶、年龄、睡眠质量指数、职业与高血压发病密切相(P<0.001);变量甘油三酯、谷丙转氨酶、年龄是高血压发病的危险因素(OR值>1,P<0.05);睡眠质量指数与高血压患病风险的非线性关系中,在拐点左边,睡眠指数每增加1个单位,高血压风险增加74%;在拐点右边,睡眠指数即使再增加,高血压的发病风险也不会继续升高。结论:睡眠质量指数与高血压患病风险呈现饱和效应。因此有助于改善目前现有的高血压防治策略,制定新的高血压防治体系及健康教育流程,提高社区卫生服务的效率及质量。

Objective:To determine the correlation between blood pressure and sleep quality by a crosssectional study in the young and middle-aged population in the Luopu community.Methods:Using PHQ-9 questionnaire and Pittsburgh sleep quality index scale(PSQI),the depression and sleep quality of the included patients were investigated.The changes in the effect value of sleep quality regression coefficient were determined through binary logistic regression.Results:The variable body mass index,uric acid,triglyceride,alanine aminotransferase,age,sleep quality index and occupation were closely related to the occurrence of hypertension(P<0.001).Variable triglyceride,alanine aminotransferase and age were risk factors for hypertension(OR>1,P<0.05).In the non-linear relationship between sleep quality index and the risk of hypertension,the risk of hypertension increased by 74%for every 1 unit increased in sleep quality index on the left side of inflection point,and the risk of hypertension did not continue to increase even if the sleep quality index increased further on the right side of inflection point.Conclusion:The correlation between sleep quality index and hypertension risk shows saturation effect.Therefore,it is helpful to improve the existing hypertension prevention and control strategies,formulate new hypertension prevention and control system and health education process,and promote the efficiency and quality of community health services.