接纳与承诺疗法联合帕罗西汀治疗无痛分娩后抑郁症的临床研究

Acceptance and commitment therapy combined with paroxetine in the treatment of postpartum depression after painless delivery: A clinical study

目的:探究接纳与承诺疗法联合帕罗西汀治疗无痛分娩后抑郁症的临床效果。方法:选取2017年5月至2018年11月本院行无痛分娩后患产后抑郁症的患者92例,按随机数字表法分为对照组(n=46)与观察组(n=46)。对照组给予帕罗西汀治疗,观察组给予接纳与承诺疗法、帕罗西汀联合治疗。对比两组疗效及治疗前后汉密尔顿抑郁量表(HAMD)、蒙哥马利-艾森贝格抑郁量表(MADRS)、汉密尔顿焦虑量表(HAMA)、自尊量表(SES)、一般自我效能感量表(GSES)、简明幸福与生活质量满意度问卷量表(Q-LES-Q-SF)评分。结果:观察组总有效率95.65%,高于对照组的76.09%(P<0.05);治疗后观察组HAMD、MADRS、HAMA评分均低于对照组(P <0. 05),SES、GSES、Q-LES-Q-SF评分均高于对照组(P <0.05)。结论:接纳与承诺疗法、帕罗西汀联合治疗无痛分娩后抑郁症,可缓解患者抑郁、焦虑情绪,提高其自尊水平、自我效能感,改善生活质量,疗效显著。

Objective:To explore the clinical efficacy of acceptance and commitment therapy(ACT)combined with paroxetine in the treatment of postpartum depression after painless delivery.Methods:A total of 92 patients with postpartum depression after painless childbirth in our hospital between January 2017 and July 2018 were randomly divided into the control group(n=46)and study group(n=46)by using the random number table.The control group was treated with paroxetine,while the study group was treated with ACT plus paroxetine.The therapeutic efficacy and scores of Hamilton Depression Scale(HAMD),Montgomery-Eisenberg Depression Scale(MADRS),Hamilton Anxiety Scale(HAMA),Self-esteem Scale(SES),General Self-efficacy Scale(GSES),Concise Well-being and Quality of Life Satisfaction Questionnaire(Q-LES-Q-SF)before and after treatment were compared between the two groups.Results:The overall effective rate was 95.65%in the study group,which was higher than that in the control group(76.09%)(P<0.05).After treatment,the HAMD,MADRS and HAMA scores were lower in the study group than those in the control group(P<0.05),the SES and GSES scores were higher in the study group than those in the control group(P<0.05),and the Q-LES-Q-SF score was higher in the study group than that in the control group(P<0.05).Conclusion:ACT plus paroxetine may relieve depression and anxiety,improve self-esteem and self-efficacy,and improve the quality of life in patients with postpartum depression after painless delivery.