高压氧治疗对脑卒中后抑郁状态和神经功能康复的影响

Effect of hyperbaric oxygenation treatment on post-stroke depression and neurological functional rehabilitation

目的探讨高压氧 (HBO)治疗对脑卒中后抑郁状态 (PSD)和神经功能康复的影响。方法 60例PSD患者随机分为治疗组和对照组 ,在常规治疗基础上 ,治疗组加用HBO治疗 ,观察并评价两组治疗前后的汉密顿抑郁量表 (HAMD)评分、临床神经功能缺损评分 (CSS)和日常生活活动能力 (ADL)评分变化。结果 1个月后 ,治疗组的HAMD评分和CSS、ADL评分均较治疗前有明显改善 (P <0 .0 1) ,而对照组治疗前后则无明显差异 (P >0 .0 5 )。结论HBO治疗可以促进PSD患者抑郁症状和神经功能的康复。

ObjectiveTo study the effect of hyperbaric oxygenation (HBO) treatment on post-stoke depression (PSD) and neurological functional rehabilitation.Methods60 patients with PSD were randomly divided into two groups, treatment group and control group. Patients in the treatment group were given HBO treatment in addition to the regular treatment. Changes of scores of Hamilton depression (HAMD), Chinese stroke scale (CSS), and activity of daily living (ADL) before and after treatment in two groups were observed and evaluated.ResultsAfter 1 month treatment scores of HAMD, CSS, and ADL in the treatment group got obviously better results than before treatment ( P<0.01). While scores in the control group had no significant difference( P>0.05).Conclusions It is suggested that HBO may improve the depressive symptom and neurological functional rehabilitation in PSD patients.