肺心病患者血清IAP及sIL-2R检测的临床意义

Clinical Significance of Detecting Serum IAP and sIL-2R Expressions in Patients with Pulmonary Heart Disease

应用一元免疫琼脂扩散法及ＥＬＩＳＡ酶联免疫检测法测定肺心病患者血清ＩＡＰ及ｓＩＬ－２Ｒ水平结果显示肺心病患者血清ＩＡＰ水平与正常对照组无显著性差异，这可能与ＩＡＰ作为免疫机能检测指标敏感性较差有关而肺心病患者血清ｓＩＬ－２Ｒ水平显著高于正常对照组，并与肺心病急性发作期有关，提示检测肺心病患者血清ｓＩＬ－２Ｒ水平可作为肺心病患者免疫机能监测的参考指标。

The serum levels of IAP and sIL-2R expressions were measured with radioimmunologic agar diffusion and ELISA assays. The results demonstrated, between the cor-pulmonale patients and normal controls, no significant difference of serum IAP, which might be attributed to the poor sensitivity of IAP as a testing marker of immunologic function. The former's serum sIL-2R level was saliently higher than the latter's and was involved with the acute attack of cor pulmonale. All this suggested that serum sIL-2R level can serve not only as a reference index monitering the immunologic function of cor-pulmonale patients but also a theoretical basis for the clinical application of immunologic preparation.