摘要
利用免疫组化方法，研究了６８例胃窦粘膜活检组织中ＩｇＧ的表达。结果表明，胃粘膜对ＨＰ感染能产生较强免疫反应，慢性胃炎的炎症反应部分是对ＨＰ抗原的一种免疫应答；在杀伤、清除ＨＰ的过程中，同时引起胃粘膜组织的免疫性损伤，是ＨＰ的致病机制之一。慢性胃炎的发生、发展可能与ＨＰ感染引起的自身免疫有关。
? The expression of Immunoglobin G of 68 antral biopsies were investigated by immunohistochemical technique. Our results showed that strong were the immune responses of the gastric mucosa to HP infection. The inflammatory reaction of chronic gastritis was partly an immune response to HP antigen. With killing and clearing HP, the immunity injury to the gastric mucosa may be the one of the pathogenic mechnism of HPpositive gastritis. The origin and development of chronic gastritis may be associated with autoimmune induced by HP.
关键词
胃炎
病因学
幽门螺旋菌
致病力
免疫化学
MeSH gastritis/ET
gastric mucosa/IM
spirochaeta/IM
spirochaeta/PY
pylorus
Immunochemistry
