中青年冠心病患者冠脉造影结果分析

Coronary angiographic feature in adult patients with coronary disease

目的 探讨中青年冠心病 (CHD)患者冠状动脉造影 (CAG)特点。方法 选年龄≤ 45岁的 5 9例CHD患者 ,分为不稳定心绞痛 (2 1例 )和心肌梗死 (38例 )两组 ,分析并对比其冠脉病变的范围和程度 ,分析心肌梗死的临床与冠脉病变的对应关系。结果 冠脉损伤以左前降支单支病变最多占 6 6 .7%,冠脉重度狭窄者多占 76 .3%,但两组间比较无显著性差异 ;有 7例CAG未见异常占 11 9%,2例系变异型心绞痛 ,5例系急性心肌梗死 ;仅有 7例存在侧支循环。结论 中青年CHD患者冠脉病变以左前降支单支受累为主 ,狭窄程度重 ,部分患者CAG正常。

Objective To study features of coronary angiography in patients, aged≤45 years, with coronary artery disease(CHD).Method According to clinical diagnosis, 59 patients were divided into two groups:unstable angina pectoris (n=21) and myocardial infarction (n=38).The branches and extents of coronary lesion in two groups were compared, and the corresponding relationship between clinical manifestation of myocardial infarction and of coronary lesion was analyzed. Results There was 66.7% of patients with single left anterior descend lesion.Serious coronary stenosis(≥75%)wasthe main(76.3%),but there was no significant difference between two groups. By angiography 7 patients(11.9%) had no any stenosis,and 2 Prinzmetal's variant angina pectoris and 5 acute myocardial infarction,either. Only 7 patients had sidebranch circulation. Conclusion Single left anterior descend lesion is the main in young adult patients with CHD, and the coronary stenosis is more serious, while coronary angiography in a minority of patients is normal.