Hox基因与胚胎种植
摘要
同源框基因是一类控制胚胎发育和细胞分化的调节基因,在人类子宫内膜存在并具周期性变化,影响子宫内膜的发育、分化及胚胎种植等过程。Hox蛋白对控制种植期子宫内膜细胞增生起重要作用。子宫内膜Hox基因的表达受性激素、细胞因子等调节。
出处
《国外医学(妇产科学分册)》
2002年第6期334-337,共4页
Foreign Medical Sciences(Obstet Gynecol Fascicle)
参考文献20
-
1Daftary GS,Taylor HS.Implantation in the human:the role of HOX genes.Semin Reprod Med,2000,18(3):311-320
-
2Zhao Y,Potter SS.Functional comparison of the Hoxa 4,Hoxa 10,and Hoxa 11 homeoboxes.Dev Biol,2002,244(1):21-36
-
3Ma L,Benson GV,Lim H,et al.Abodminal B (AbdB)Hoxa genes:regulation in adult uterus by estrogen and progesterone and repression in Mullerian duct by the synthetic estrogene diethylstibestrol(DES).Dev Biol,1998,197(2):141-154
-
4Trainor PA,Sobieszczuk D,Wilkinson D,et al.Signalling between the hindbrain and paraxial tissues dictates neural crest migration pathways.Development,2002,129(2):433-442
-
5Ayton P,Sneddon SF,Palmer DB,et al.Truncation of the Mll gene in exon 5 by gene targeting leads to early preim-plantation lethality of homozygous embryos.Genesis,2001,30(4):201-212
-
6Ma L,Yao M,Maas RL.Genetic control of uterine receptivity during implantation.Semin Reprod Endocrinol,1999,17(3):205-216
-
7Taylor HS,Arici A,Olive D,et al.HOXA10 is expressed in response to sex steroids at the time of implantation in the human endometrium.J Clin Invest,1998,101(7):1379-1384
-
8Cermik D,Karaca M,Taylor HS.HOXA10 expression is repressed by progesterone in the myometrium:differential tissue-specific regulation of HOX gene expression in the reproductive tract.J Clin Endocrinol Metab,2001,86(7):3387-3392
-
9Osborne J,Hu C,Hawley C,et al.Expression of HOXD10 gene in normal endometrium and endometrial adenocarcinoma.J Soc Gynecol Investig,1998,5(5):277-280
-
10Taylor HS,Bagot C,Kardana A,et al.HOX gene expression is altered in endometrium of women with endometriosis.Hum Reprod,1999,14(5):1328-1331
-
1樊建设.维生素A和同源框基因与胚胎发育[J].国外医学(遗传学分册),1999,22(6):302-305. 被引量:4
-
2冉伶,刘文君.HOX基因参与造血调控的研究进展[J].中国小儿血液,2005,10(1):37-39.
-
3严兆丹,薛金娥,徐焱成,郭敏.p22phox基因多态性与2型糖尿病肾病的相关性研究[J].医学新知,2005,15(2):17-20.
-
4李斌,丰有吉.激素对女性生殖道组织Hox基因表达的调控[J].国际生殖健康/计划生育杂志,2008,27(1):30-33.
-
5王莉芬,罗宏志,朱正美,王介东.同源框基因与着床[J].生殖与避孕,1999,19(6):323-327. 被引量:4
-
6龙乾发,刘卫平.bHLH和Hox基因对GABA能神经元诱导分化研究进展[J].中华神经外科疾病研究杂志,2010,9(6):564-566. 被引量:2
-
7杨俊杰.HOX基因与造血细胞发育[J].国外医学(生理病理科学与临床分册),1998,18(4):324-326.
-
8陈辉.HOXA10与雌性生殖[J].国外医学(计划生育分册),2003,22(1):27-31.
-
9邬国军,陈利玉,戴橄,姚孟辉,陈淑贞,舒明星,罗敏华.人类巨细胞病毒感染对神经胶质瘤细胞HOXB5,HOXB6,HOXB7及HOXB8基因表达的影响[J].湖南医科大学学报,2001,26(5):409-411. 被引量:3
-
10吴瑞瑾,周馥贞.IGF系统在子宫内膜的表达及其与种植的关系[J].国外医学(妇产科学分册),2002,29(5):304-307.